MCQ Test body { font-family: Arial, sans-serif; margin: 20px; } .question { margin-bottom: 20px; } .tick { color: green; /* Green color for tick mark */ font-weight: bold; } .question-title { font-weight: bold; /* Bold the questions */ }
201. To be antigen, the chemical molecule (protein) needs:
A. High molecular weight
B. Chemical complexity
C. Both “A” and “B”
D. Nucleic acid
202. The immunity acquired by inoculation of living organism of attenuated virulence is:
A. Artificial active immunity
B. Passive immunity
C. Natural active immunity
D. Local immunity
203. Fluid extruded from clotted blood is known as ____.
A. Plasma
B. Serum
C. buffy coat
D. Lymph
204. Which PRR recognizes distinct molecular structures, abundant to many cells and there is ten in humans?
A. Nod-like receptors
B. RIG-like receptors
C. Toll-like receptors
D. PAMP of neutrophils
205. A signaling molecule from microbes recognized by phagocytes is:
A. Complement
B. PAMP
C. Pyrogen
D. Lectin
206. Which of the following is NOT produced by phagocytes?
A. Hydroxyl radical
B. Superoxide anion
C. Hydrogen peroxide
D. Bradykinin
207. Acquired / adaptive immune cells include?
A. Lymphocytes
B. Eosinophils
C. Basophils
D. Neutrophils
208. Reproduction in bacteria occurs by:
A. Budding
B. Bursting
C. Binary Fission
D. Fragmentation
209. Bacteria eating viruses are known as:
A. Phagocytes
B. Viricides
C. Prophages
D. Bacteriophages
210. Which of the following is Gram-positive bacteria?
A. Staphylococcus
B. E. coli
C. Salmonella
D. Pseudomonas
211. In plasmid DNA isolation, ____________ is used to neutralize the solution, enabling DNA to renature.
A. NaCl
B. potassium acetate
C. acetic acid
D. All of these
212. In genomic DNA isolation, disruption of nucleoproteins and degradation of proteins is carried out by:
A. SDS
B. proteinase K
C. isopropanol
D. Alcohol
213. Streptococci are classified according to:
A. their cell walls antigens
B. reaction on blood agar
C. toxin production
D. Both “A” and “B”
214. Selective media for TB bacilli is:
A. NNN media
B. Lowenstein–Jensen (LJ) medium
C. Mannitol Salt Agar (MSA)
D. MacConkey media
215. Widal test is used for:
A. Typhoid fever
B. Salmonella
C. Brucellosis
D. All of these
216. All of the Salmonellae are motile EXCEPT:
A. S. typhi
B. S. enteridis
C. S. gallinarum
D. S. chester
217. Ascoli’s test helps to confirm lab diagnosis of _____.
A. Tetanus
B. Anthrax
C. Typhoid
D. Cholera
218. Transfection is insertion of DNA into ______ cells.
A. bacterial
B. eukaryotic
C. Viruses
D. Both “A” and “B”
219. In agarose gel electrophoresis, loading buffer gives ___________ to sample.
A. Color
B. Density
C. Shade
D. Both “A” & “B”
220. The virulence factor of botulism is a/an_______.
A. Endotoxin
B. Enterotoxin
C. Neurotoxin
D. Hemolysin enzyme
221. Which of the following is a spirochete?
A. Gonococci
B. Treponema
C. Staphylococcus
D. Streptococcus
222. Once the Phagosome and lysosome fuse, the structure is known as:
A. Lysophagosome
B. Macrophage
C. Membrane attack complex
D. Phagolysosome
223. T-lymphocytes mature in which tissue/organ?
A. Thyroid
B. Bone marrow
C. Thymus
D. Tonsils
224. Place following events of phagocytosis in the order. 1.Chemotaxis 2.Ingestion 3.Digestion 4.Attachment
A. 1,2,4,3.
B. 4,1,2,3.
C. 1,4,2,3.
D. 4,2,3,1.
225. An enzyme found in our tears, saliva, serum, and mucus that degrades the peptidoglycan of the cell wall of Gram-positive bacteria is called?
A. Amylase
B. Lysozyme
C. Keratinase
D. Peptidase
226. Internalization of the pathogen via endocytosis encase the pathogen in a membrane vacuole known as a?
A. Lipid bilayer
B. Lysosome
C. Phagosome
D. Phagolysosome
227. Which of the following is primarily human pathogenic bacteria?
A. S. typhi
B. E. coli
C. S. aureus
D. Mycobacterium
228. An enrichment medium for Salmonella is ________.
A. Alkaline peptone water
B. MacConkey broth
C. Nutrient broth
D. Selenite F broth
229. TE buffer functions as:
A. Maintain pH
B. Block endonucleases
C. Both “A” and “B”
D. Denature proteins
230. Agarose gel electrophoresis is a widely-used method that separates molecules based on:
A. Electrical charge
B. Size
C. Shape
D. All of these
231. Which are components of INNATE IMMUNITY in respiratory system?
1. mucus 2. mucociliary escalator 3. normal flora 4. lysozyme 5. acidic environment
A. 1,2,5.
B. 1,3.
C. 1,2,3,4.
D. 1,2,3.
232. 0.7% agarose gel provides good resolution for _______ DNA, while 2% gel for ________ DNA.
A. Large, small
B. small, large
C. Both ‘A’ & ‘B’
D. None of these
233. Innate immunity involves all EXCEPT?
A. Anatomical barriers
B. Phagocytosis
C. Inflammatory mechanisms
D. Antibody production
234. You enter a dusty room, feel an itch in your nose, and sneeze. This is an example of the operation of which of the following innate immune mechanism?
A. The low pH of the environment.
B. The physical barrier produced by hairs.
C. Phagocytosis by macrophages.
D. Mucus joint with movement of cilia of lining cells
235. Which of the following is a distinction between the innate and adaptive immune systems?
A. Only one system to produce cytokines.
B. Antigenic specificity in only one system.
C. Only one system to recognize virally infected cells.
D. Only one system to mediate cell cytotoxicity.
236. Stomach clears out pathogens by?
A. Secreting HCl
B. Normal microflora
C. Phagocytosis
D. All of these
237. Kupffer cells are macrophages found in_______.
A. Lung
B. Bone
C. Kidney
D. Liver
238. Temperature rising chemicals are?
A. Thermogens
B. Pyrogens
C. Pyogenic
D. All of these
239. Physical barriers of immune system are:
A. Skin and the mucosal membranes.
B. Skin, body temperature and mucosal membranes.
C. Skin, inflammation and the mucosal membranes.
D. The bones and the mucosal membranes.
240. Chemical barriers include:
A. Tears, sweat, saliva, stomach acid and feces.
B. Tears, breast milk, sweat, saliva, stomach acid.
C. Hair, breast milk, sweat, saliva, stomach acid.
D. Tears and urine.
241. Interferons protect which of the following?
A. Only viral infected cells
B. Only bacterial infected cells
C. Healthy host cells
D. Blood cells
242. RNA contains:
A. Alanine
B. Thymidine
C. Uracil
D. Arginine
243. Time taken for a bacterium to multiple from 1 to 2?
A. Incubation time
B. Growth rate
C. Generation time
D. Both “B” and “C”
244. Self-replicating, small circular DNA molecules present in bacterial cell are known:
A. Plasmids
B. Cosmids
C. Plasmomeros
D. Plastids
245. Some of the dust particles are not expelled by sneeze and make their way further down the respiratory tract but not yet into the alveolar space. Here their elimination is the job of which of the following?
A. Released granular contents of your granulocytes.
B. The low pH of the environment.
C. The physical barrier produced by hairs.
D. Mucus joint with movement of cilia of lining cells
246. Formation of proteins in ribosomes occur through process known as:
A. Central dogma
B. Transcription
C. Translation
D. Both “A” and “C”
247. Mostly bacteria grow in aerobic conditions, but some require more CO2 for their growth, these are known as:
A. Halophiles
B. Acidophiles
C. Capnophiles
D. Hyperthermophiles
248. Transfer of antibodies from mother to her baby through breast milk is example of:
A. Active natural acquired immunity
B. Passive artificial acquired immunity
C. Passive natural acquired immunity
D. Active artificial acquired immunity
249. Penicillin is an antibiotic obtained from?
A. A capsular bacterium
B. A yeast
C. A fungus
D. An alga
250. Viruses that infect bacteria are known as ________.
A. virons
B. bacteroids
C. bacteriophages
D. retrovirurses
251. The Kingdom of recyclers is known as _____.
A. Algae
B. Bacteria
C. Fungi
D. Embryophata
252. Unicellular yeast cells reproduce by _______.
A. Sporing
B. Conidiation
C. Budding
D. Both “A” and “B”
253. Interferons protect healthy cells by production of?
A. Antibacterial proteins
B. Antifungal proteins
C. Antiviral proteins
D. Antiprotozoal proteins
254. Branch of Microbiology related with study of fungi:
A. Protozoology
B. Phycology
C. Mycology
D. Biotechnology
255. Penicillin acts by inhibiting:
A. Cell wall synthesis
B. RNA synthesis
C. Folate synthesis
D. DNA gyrase
256. Schizogony is mode of reproduction in:
A. Algae
B. Protozoa
C. Fungi
D. Embryophata
257. Disease that effects many people at different countries is termed as:
A. Sporadic
B. Epidemic
C. Pandemic
D. Endemic
258. Some bacteria form dormant structure during harsh environmental conditions is known as:
A. Endospore
B. Capsule
C. Cyst
D. Bud
259. Many clostridial diseases require a/an _________ environment for their development.
A. living tissue
B. anaerobic
C. aerobic
D. low-pH
260. Bacterial cells multiply rapidly during:
A. Lag phase
B. Log phase
C. Death phase
D. Stationary phase
261. A group of fungal hyphae are called ______.
A. Filtering body
B. Mycelia
C. Conidia
D. Yeast
262. Most human pathogenic bacteria are:
A. Psychrophiles
B. Psychrotrophes
C. Thermophiles
D. Mesophiles
263. DNA contains:
A. Alanine
B. Thymine
C. Uracil
D. Arginine
264. Type of immunity through vaccination is:
A. Active natural acquired immunity
B. Passive artificial acquired immunity
C. Passive natural acquired immunity
D. Active artificial acquired immunity
265. Shrinkage of the cell occur in ______ environment.
A. Hypotonic
B. Hypertonic
C. Isotonic
D. Both “A” and “C”
266. Bacterium is ________ type of organism.
A. Prokaryotic
B. Eukaryotic
C. Acellular
D. May be prokaryotic or eukaryotic
267. Botulin toxin prevents release of what chemical that initiates the signal for muscle contraction?
A. Serotonin
B. Acetylcholine
C. Dopamine
D. Norepinephrine
268. An infection peculiar to swine causes _______ when transmitted to humans.
A. Anthrax
B. Diphtheria
C. Tuberculosis
D. Erysipeloid
269. ____ DOES NOT predispose to gas gangrene?
A. Surgical incisions
B. Compound fractures
C. Puncture wounds
D. Dislocated shoulder
270. In general, humans are rather prone to ____ with tubercle bacillus but are resistant to ____?
A. disease, infection
B. infection, disease
C. TB, Leprosy
D. Leprosy, TB
271. Malaria is caused by pathogen known as ______.
A. Plasmodium
B. Paramecium
C. Pseudomonas
D. Pasteurella
272. First phase of a bacterial growth curve is
A. Log phase
B. Lag phase
C. γ phase
D. Exponential
273. Spirochete bacteria move with the help of:
A. Pseudopodia
B. Axial filament
C. Endoflagella
D. Both “B” and “C”
274. Viruses are:
A. Living
B. Non-Living
C. Only living inside cells
D. Capsular
275. All of the following prokaryotes are bounded by a cell wall EXCEPT?
A. Spirochetes
B. Actinomycetes
C. Mycoplasma
D. Streptococcus
276. Tubercles are granulomas with a central core containing TB bacilli and enlarged ______.
A. Neutrophils
B. Lymphocytes
C. Eosinophils
D. Macrophages
277. Conversion of DNA to RNA is:
A. Transcription
B. Transduction
C. Translation
D. Replication
278. The bases Adenine and Thymine are paired with:
A. Double hydrogen bonds
B. Single hydrogen bonds
C. Triple hydrogen bonds
D. Both “B” and “C”
279. Fungi reproduce by:
A. Sexual Spores
B. Fragmentation
C. Asexual spores
D. All of these
280. For TB control, vaccine is based on attenuated “Bacille Calmette-Guérin” (BCG) strain of _______.
A. Mycobacterium tuberculosis
B. Mycobacterium avium complex
C. Mycobacterium bovis
D. Mycobacterium paratuberculosis
281. Antibiotics are the drugs which commonly kill?
A. Bacteria
B. Virus
C. Algae
D. Protozoa
282. Genital herpes is caused by?
A. HSV-1
B. HSV-2
C. HSV-3
D. HSV-4
283. Blood agar is an example of:
A. Enrichment media
B. Selective media
C. Enriched media
D. General purpose media
284. A mutation that produces termination codon is:
A. Mis-sense mutation
B. Reverse mutation
C. Non-sense mutation
D. Frame shift mutation
285. Gas gangrene bacillus is:
A. Facultative anaerobe
B. Obligate aerobe
C. Facultative aerobe
D. Obligate anaerobe
286. If vector ONLY transmits pathogen is called:
A. Biological vector
B. Biological reservoir
C. Biological carrier
D. Mechanical vector
287. What genus of organisms is important as decomposers and involve in bioremediation?
A. Pseudomonas
B. Brucella
C. Francisella
D. Bordetella
288. Brucellosis is spread from human to human contact with ALL BUT which of the following?
A. Blood
B. Urine
C. Placenta
D. Cerebrospinal fluid
289. What enzyme possessed by Helicobacter pylori helps to neutralize stomach acid?
A. Coagulase
B. Urease
C. Hyaluronidase
D. DNase
290. The technique used to kill all microorganisms is:
A. Disinfection
B. Sterilization
C. Antisepsis
D. Pasteurization
291. Glassware are sterilized by:
A. Hot air oven
B. Autoclave
C. Incineration
D. Boiling
292. ________ CAN NOT be found in the lymph node?
A. Lymphoid follicle
B. B cells
C. Red pulp
D. T cells
293. Virulence of tubercle bacillus is due to _______ that avoid destruction by lysosomes/macrophages.
A. Exotoxin
B. Cord factor
C. Enterotoxin
D. Endotoxin
294. The form of leprosy associated with severe disfigurement of the face is:
A. Tuberculoid
B. Lepromatous
C. Borderline
D. Papular
295. Diphtheria is caused by:
A. Staphylococcus
B. Corynebacterium
C. Bacillus
D. Clostridium
296. ______ reside in sebaceous glands in human skin?
A. Bacillus
B. Propionibacterium
C. Erysipelothrix
D. Corynebacterium
297. The largest virus is:
A. Parvo virus
B. Picorna virus
C. Pox virus
D. HIV
298. Endospores can be stained with:
A. Malachite green
B. Safranin
C. Methylene blue
D. Crystal Violet
299. All of the following are DNA viruses EXCEPT:
A. Parvo virus
B. Pox virus
C. Polio virus
D. Hepatitis B Virus
300. Comparing the two, Actinomyces ______ sulfur granules and Nocardia is _______.
A. Form; Acid-fast
B. Form; Not acid-fast
C. Does not form; Acid-fast
D. Does not form; Not acid-fast
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