Histopathology Stains MCQs
- 1. Which stain is used for visualizing collagen fibers?
- A. Hematoxylin
- B. Eosin
- C. Masson’s Trichrome ✅
- D. Alcian Blue
- 2. What is the primary use of Hematoxylin and Eosin (H&E) stain?
- A. To identify microorganisms
- B. To differentiate cellular and extracellular components ✅
- C. To stain glycogen
- D. To highlight lipids
- 3. Which stain is specific for acidic mucopolysaccharides?
- A. Periodic Acid-Schiff (PAS)
- B. Alcian Blue ✅
- C. Congo Red
- D. Reticulin Stain
- 4. Which stain is used for visualizing mycobacteria?
- A. Gram Stain
- B. Ziehl-Neelsen Stain ✅
- C. Silver Stain
- D. Giemsa Stain
- 5. What is the main application of Periodic Acid-Schiff (PAS) stain?
- A. To detect glycogen and mucosubstances ✅
- B. To highlight muscle fibers
- C. To stain bacteria
- D. To visualize lipid droplets
- 6. Which stain is commonly used to detect amyloid deposits?
- A. Oil Red O
- B. Congo Red ✅
- C. PAS Stain
- D. Giemsa Stain
- 7. What is the characteristic color of nuclei when stained with Hematoxylin?
- A. Red
- B. Blue ✅
- C. Green
- D. Yellow
- 8. Which stain is used for fungal detection in tissue sections?
- A. Gram Stain
- B. Gomori Methenamine Silver (GMS) Stain ✅
- C. PAS Stain
- D. Alcian Blue
- 9. Which stain highlights reticular fibers in tissues?
- A. Reticulin Stain ✅
- B. H&E Stain
- C. Silver Stain
- D. PAS Stain
- 10. What is the primary purpose of Sudan Black stain?
- A. To identify lipids ✅
- B. To stain glycogen
- C. To visualize fungi
- D. To detect collagen
- 11. Which stain is used for detecting Helicobacter pylori in tissues?
- A. Giemsa Stain ✅
- B. Gram Stain
- C. PAS Stain
- D. Ziehl-Neelsen Stain
- 12. Which stain is used to detect iron deposits in tissues?
- A. Masson’s Trichrome
- B. Prussian Blue ✅
- C. Alcian Blue
- D. H&E Stain
- 13. What does Toluidine Blue specifically stain?
- A. Nuclei
- B. Mast cell granules ✅
- C. Collagen
- D. Fungi
- 14. Which stain is used to highlight elastic fibers in tissues?
- A. Masson’s Trichrome
- B. Van Gieson’s Stain ✅
- C. Alcian Blue
- D. PAS Stain
- 15. What color does eosin stain cytoplasm?
- A. Blue
- B. Red ✅
- C. Green
- D. Black
- 16. Which stain is used to detect glycogen in tissues?
- A. Oil Red O
- B. PAS Stain ✅
- C. GMS Stain
- D. Alcian Blue
- 17. What is the purpose of Orcein stain?
- A. To highlight mucins
- B. To detect elastic fibers ✅
- C. To stain collagen
- D. To stain fungi
- 18. Which stain is used for detecting nerve fibers?
- A. Luxol Fast Blue ✅
- B. Sudan Black
- C. PAS Stain
- D. H&E Stain
- 19. What does the Gram stain differentiate?
- A. Acid-fast bacteria
- B. Gram-positive and Gram-negative bacteria ✅
- C. Fungi and bacteria
- D. Nucleic acids
- 20. What is the role of eosin in the H&E stain?
- A. To stain nuclei
- B. To stain cytoplasmic structures ✅
- C. To detect lipids
- D. To stain elastic fibers
- 21. Which stain is used for melanin visualization?
- A. Fontana-Masson Stain ✅
- B. PAS Stain
- C. GMS Stain
- D. Congo Red
- 22. Which stain is used for lipids in frozen tissue sections?
- A. Oil Red O ✅
- B. H&E Stain
- C. PAS Stain
- D. Giemsa Stain
- 23. What does Methenamine Silver stain highlight?
- A. Collagen fibers
- B. Fungi and basement membranes ✅
- C. Lipids
- D. Iron deposits
- 24. Which stain is commonly used for blood smears?
- A. Wright-Giemsa Stain ✅
- B. PAS Stain
- C. Alcian Blue
- D. Prussian Blue
- 25. Which stain is ideal for basement membrane visualization?
- A. Methenamine Silver ✅
- B. PAS Stain
- C. Masson’s Trichrome
- D. Reticulin Stain
