Histopathology of Infectious Diseases MCQs
- 1. What is a common histopathological feature seen in tissues infected with Mycobacterium tuberculosis?
- A. Granulomatous inflammation with caseous necrosis ✅
- B. Neutrophilic abscesses
- C. Necrosis without inflammation
- D. Lymphocytic infiltration
- 2. In histopathology, what is typically observed in tissue infected with Candida species?
- A. Pseudohyphae and budding yeast cells ✅
- B. Granuloma formation
- C. Multinucleated giant cells
- D. Fibrosis and necrosis
- 3. What histopathological feature is characteristic of syphilis?
- A. Granulomas with gumma formation ✅
- B. Pseudohyphal forms
- C. Necrosis with neutrophilic infiltration
- D. Lymphocyte-rich infiltrates
- 4. What is a key histopathological finding in tissues infected by the Human Immunodeficiency Virus (HIV)?
- A. Lymphocytic depletion and lymphoid follicle destruction ✅
- B. Caseous necrosis
- C. Lymphocytic infiltration and granulomas
- D. Neutrophilic abscess formation
- 5. Which histopathological feature is commonly seen in tissues infected with the Epstein-Barr virus (EBV)?
- A. Reed-Sternberg cells
- B. Hodgkin’s lymphoma cells
- C. B-cell proliferation and mononucleosis-like changes ✅
- D. Granulomatous inflammation
- 6. Which histopathological change is typically observed in tissues infected with Herpes Simplex Virus (HSV)?
- A. Multinucleated giant cells and intranuclear inclusion bodies ✅
- B. Lymphocytic infiltration
- C. Granulomatous inflammation
- D. Necrosis with neutrophil infiltration
- 7. What is a typical histopathological finding in tissue infected by Treponema pallidum (syphilis)?
- A. Pseudohyphal forms and yeast cells
- B. Perivascular lymphocytic infiltrates and endarteritis obliterans
- C. Granuloma formation with gummas ✅
- D. Necrotic tissue and neutrophilic infiltrates
- 8. Which feature is characteristic of histopathology in the early stages of a viral infection?
- A. Cytoplasmic inclusion bodies
- B. Necrosis and inflammatory cell infiltration ✅
- C. Caseous necrosis
- D. Hyperplasia of endothelial cells
- 9. What histological change is observed in tissue infected with bacteria like Salmonella?
- A. Formation of granulomas
- B. Neutrophil infiltration and abscess formation ✅
- C. Lymphocytic infiltration and fibrosis
- D. Caseous necrosis and fibrosis
- 10. What is the main feature seen in tissues affected by Clostridium botulinum?
- A. Necrosis of muscle fibers and neurotoxicity ✅
- B. Pseudomembranous inflammation
- C. Granulomatous inflammation
- D. Tissue hyperplasia
- 11. Which of the following is a common histopathological feature of tissue infected with Helicobacter pylori?
- A. Gastric mucosal inflammation and lymphocytic infiltration ✅
- B. Granuloma formation
- C. Formation of abscesses
- D. Pseudohyphal forms
- 12. What histopathological feature is commonly associated with chronic viral infections?
- A. Necrosis with neutrophil infiltration
- B. Fibrosis and cellular infiltrates, including lymphocytes ✅
- C. Granuloma formation with caseous necrosis
- D. Microvascular injury and thrombosis
- 13. In histopathology, what is a typical feature of a tissue infected with Chlamydia trachomatis?
- A. Cytoplasmic inclusion bodies and epithelial cell necrosis ✅
- B. Granulomatous inflammation
- C. Abscess formation and neutrophil infiltration
- D. Fibrosis and scarring
- 14. Which histopathological feature is observed in tissues infected with the Varicella-Zoster virus?
- A. Intranuclear inclusions and multinucleated giant cells ✅
- B. Lymphocytic infiltration and necrosis
- C. Granulomatous inflammation
- D. Neutrophilic abscesses
- 15. What histological feature is typical of tissue infected by Staphylococcus aureus?
- A. Formation of abscesses and pus formation ✅
- B. Caseous necrosis
- C. Granulomatous inflammation
- D. Fibrosis and tissue scarring
