Histopathology of Inflammatory Diseases MCQs
- What is a characteristic feature of acute inflammation in tissue samples?
- A. Granuloma formation
- B. Neutrophil infiltration ✅
- C. Lymphocyte infiltration
- D. Fibrosis
- Which of the following cells are predominantly involved in chronic inflammation?
- A. Neutrophils
- B. Eosinophils
- C. Macrophages and lymphocytes ✅
- D. Basophils
- In the histopathology of granulomatous inflammation, which structure is typically observed?
- A. Abscess formation
- B. Multinucleated giant cells ✅
- C. Necrotic tissue
- D. Tissue fibrosis
- Which of the following conditions is characterized by granulomatous inflammation?
- A. Rheumatoid arthritis
- B. Tuberculosis ✅
- C. Psoriasis
- D. Asthma
- What histological feature is commonly seen in acute inflammation?
- A. Formation of granulomas
- B. Presence of neutrophils and edema ✅
- C. Fibrosis and collagen deposition
- D. Lymphocyte infiltration
- In tissue samples showing chronic inflammation, what cellular feature is often observed?
- A. Presence of neutrophils
- B. Increased vascularity and fibrosis
- C. Macrophages and lymphocytes ✅
- D. Absence of cell infiltrates
- Which inflammatory condition is associated with the formation of pannus in joint tissues?
- A. Rheumatoid arthritis ✅
- B. Systemic lupus erythematosus
- C. Psoriatic arthritis
- D. Osteoarthritis
- What is a common histological finding in tissue samples from patients with systemic lupus erythematosus (SLE)?
- A. Granuloma formation
- B. Vascular injury and immune complex deposition ✅
- C. Necrosis of tissue
- D. Edema and neutrophil infiltration
- What histopathological feature is characteristic of tissue samples from patients with ulcerative colitis?
- A. Crypt abscesses and mucosal ulceration ✅
- B. Granulomas with caseous necrosis
- C. Thickened, fibrotic submucosa
- D. Giant cell formation
- In which disease is a “butterfly rash” often observed along with systemic inflammation?
- A. Rheumatoid arthritis
- B. Systemic lupus erythematosus (SLE) ✅
- C. Psoriasis
- D. Dermatomyositis
- What is the primary role of mast cells in inflammatory reactions?
- A. Release of histamine and cytokines to promote inflammation ✅
- B. Phagocytosis of pathogens
- C. Formation of granulomas
- D. Regulation of T-cell responses
- In which condition would you expect to see significant eosinophil infiltration in tissue samples?
- A. Asthma and allergic reactions ✅
- B. Rheumatoid arthritis
- C. Tuberculosis
- D. Crohn’s disease
- What histopathological change is observed in tissue samples from patients with acute myocardial infarction?
- A. Granuloma formation
- B. Necrosis of myocardial cells and infiltration of neutrophils ✅
- C. Fibrosis and collagen deposition
- D. Proliferation of endothelial cells
- Which immune cells are primarily involved in the pathogenesis of multiple sclerosis?
- A. Neutrophils
- B. T-cells and macrophages ✅
- C. Eosinophils
- D. Basophils
- What histopathological finding is common in granulomatous diseases like tuberculosis?
- A. Necrosis and caseous material ✅
- B. Lymphocytic infiltration
- C. Microvascular injury
- D. Edema and neutrophil activity
