Blood Banking MCQs:

These 300+ multiple-choice questions (MCQs) are designed to test your knowledge and understanding of various aspects of blood banking, a critical component of transfusion medicine. Blood banking involves the collection, processing, testing, storage, and distribution of blood and blood components to ensure their safe and effective use in medical treatments. The questions cover a wide range of topics, including blood typing, compatibility testing, transfusion reactions, blood component therapy, and the management of adverse events. By answering these questions, you will gain a deeper insight into the complexities and importance of blood banking in modern healthcare.

MCQ Test
51. A father donating platelets for his son is connected to a continuous flow machine, which uses the principle of centrifugation to separate platelets from whole blood. As the platelet are harvested, all other remaining elements are returned to the donor. This method of platelet collection is known as:
A. apheresis
B. autologous
C. homologous
D. fractionation
52. To qualify as a donor for autologous transfusion a patient’s hemoglobin should be at least:
A. 8g/dL (80g/L)
B. 11g/dL (110g/L)
C. 13g/dL (130g/L)
D. 15g/dL (150g/L)
53. What is/are the minimum pretransfusion testing requirement(s) for autologous donations collected and transfused by the same facility?
A. ABO and Rh typing only
B. ABO/Rh type, antibody screen
C. ABO/Rh type, antibody screen, crossmatch
D. no pretransfusion testing is required for autologous donations
54. In a quality assurance program, cryoprecipitated AHF must contain a minimum of how many international units of Factor VIII?
A. 60
B. 70
C. 80
D. 90
55. An assay of plasma from a bag of cryoprecipitated AHF yields a concentration of 9 international units (IU) of Factor VIII per mL of cryoprecipitated AHF. If the volume is 9 mL, what is the Factor VIII content of the bag in IU?
A. 9
B. 18
C. 27
D. 81
56. Refer to the following table:
Antigens 1 2 3 4 5 Test results
I + 0 0 + + +
II 0 0 + 0 + 0
III 0 + + + 0 0
IV 0 + + 0 + +
V + + + 0 0 +
auto 0
Given the most probable genotypes of the parents, which of the following statements best describes the most probable Rh genotypes of the 4 children?
A. 2 are R1r, 2 are R1R1
B. 3 are R1r, 1 is rr
C. 1 is Ror, 1 is R1r, 2 are R1R1
D. 1 is Ror, 1 R1R1, 2 are R1r
57. The linked HLA genes on each chromosome constitute a(n):
A. allele
B. trait
C. phenotype
D. haplotype
58. An individual’s red blood cells give the following reactions with Rh antisera:
anti-D anti-C anti-E anti-c anti-e Rh control
4+ 3+ 0 3+ 3+ 0
The individual’s most probable genotype is:
A. DCe/DcE
B. DcE/dce
C. Dce/dce
D. DCe/dce
59. A blood donor has the genotype: hh,AB. What is his red blood cell phenotype?
A. A
B. B
C. O
D. AB
60. An individual has been sensitized to the k antigen and has produced anti-k. What is her most probable Kell system genotype?
A. KK
B. Kk
C. kk
D. K0K0
61. Given the following typing results, what is this donor’s racial ethnicity?
Le(a-b-); Fy(a-b-); Js(a+b+)
a. African american
A. African american
B. Asian American
C. Native American
D. Caucasian
62. A mother has red cell phenotype D+C+E-c-e+ with anti-c (titer of 32 at AHG) in her serum. The father has the phenotype D+C+E-c+e+. The baby is Rh-negative and not affected with hemolytic disease of the newborn. What is the baby’s most probable Rh genotype?
A. r’r’
B. r’r
C. R1R1
D. R1r
63. In the emergency situation, Rh-negative red cells are transfused into an Rh-positive person of the genotype CDe/CDe. The first antibody most likely to develop is:
A. anti-c
B. anti-d
C. anti-e
D. anti-E
64. Most blood group systems are inherited as:
A. sex-linked dominant
B. sex-linked recessive
C. autosomal recessive
D. autosomal codominant
65. The mating of an Xg(a+) man and an Xg(a-) woman will only produce:
A. Xg(a-) sons and Xg(a-) daughters
B. Xg(a+) sons and Xg(a+) daughters
C. Xg(a-) sons and Xg(a+) daughters
D. Xg(a+) sons and Xg(a-) daughters
66. Refer to the following data:
anti-C anti-D anti-E anti-c anti-e
+ + + + +
Given the reactions above, which is the most probable genotype?
A. R1R1
B. R1r’
C. R0r”
D. R1R2
67. A patient’s red cells type as follows:
anti-D anti-C anti-E
4+ 0 0
Which of the following genotype would be consistent with these results?
A. R0R0
B. R2r”
C. R1R2
D. Rzr
68. The red cells of a nonsecretor (se/se) will most likely type as:
A. Le(a-b-)
B. Le(a+b+)
C. Le(a+b-)
D. Le(a-b+)
69. Which of the following phenotypes will react with anti-f?
A. rr
B. R1R1
C. R2R2
D. R1R2
70. A patient’s red blood cells gave the following reactions:
anti-D anti-C anti-E anti-c anti-e anti-f
+ + + + + 0
The most probable genotype of this patient is:
A. R1R2
B. R2r”
C. Rzr
D. RzRz
71. Anti-N is identified in a patient’s serum. If random crossmatches are performed on 10 donor units, how many would be expected to be compatible?
A. 0
B. 3
C. 7
D. 10
72. A woman types as Rh-positive. She has an anti-c titer of 32 at AHG. Her baby has a negative DAT and is not affected by hemolytic disease of the newborn. What is the father’s most likely Rh phenotype?
A. rr
B. r”r
C. R1r
D. R2r
73. Which of the following red cell typings are most commonly found in the African American donor population?
A. Lu(a-b-)
B. Jk(a-b-)
C. Fy(a-b-)
D. K-k-
74. Four units of blood are needed for elective surgery. The patient’s serum contains anti-C, anti-e, anti-Fya and anti-Jkb. Which of the following would be the best source of donor blood?
A. test all units in current stock
B. test 100 group O, Rh-negative donors
C. test 100 group compatible donors
D. rare donor file
75. A donor is tested with Rh antisera with the following results:
anti-D anti-C anti-E anti-c anti-e Rh control
+ + 0 + + 0
What is his most probable Rh genotype?
A. R1R1
B. R1r
C. R0r
D. R2r
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