Blood Banking MCQs:
These 300+ multiple-choice questions (MCQs) are designed to test your knowledge and understanding of various aspects of blood banking, a critical component of transfusion medicine. Blood banking involves the collection, processing, testing, storage, and distribution of blood and blood components to ensure their safe and effective use in medical treatments. The questions cover a wide range of topics, including blood typing, compatibility testing, transfusion reactions, blood component therapy, and the management of adverse events. By answering these questions, you will gain a deeper insight into the complexities and importance of blood banking in modern healthcare.
26. According to the AABB standards, Fresh Frozen Plasma must be infused within what period of time following thawing?
A. 24 hours
B. 36 hours
C. 48 hours
D. 72 hours ✅
A. 24 hours
B. 36 hours
C. 48 hours
D. 72 hours ✅
27. Cryoprecipitate AHF, is maintained in the frozen state at -18oC or below, has a shelf life of:
A. 42 days
B. 6 months
C. 12 months ✅
D. 36 months
A. 42 days
B. 6 months
C. 12 months ✅
D. 36 months
28. Once, thawed, Fresh Frozen Plasma must be transfused within:
A. 4 hours
B. 8 hours
C. 12 hours
D. 24 hours ✅
A. 4 hours
B. 8 hours
C. 12 hours
D. 24 hours ✅
29. An important determinant of platelet viability following storage is:
A. Plasma potassium concentration
B. Plasma pH ✅
C. Prothrombin time
D. Activated partial thromboplastin time
A. Plasma potassium concentration
B. Plasma pH ✅
C. Prothrombin time
D. Activated partial thromboplastin time
30. In the liquid state, plasma must be stored at:
A. 1o-6oC ✅
B. 22oC
C. 37oC
D. 56oC
A. 1o-6oC ✅
B. 22oC
C. 37oC
D. 56oC
31. During storage, the concentration of 2,3-diphosphoglycerate (2,3-DPG) decreases in a unit of:
A. Platelets
B. Fresh Frozen Plasma
C. Red Blood Cells ✅
D. Cryoprecipitated AHF
A. Platelets
B. Fresh Frozen Plasma
C. Red Blood Cells ✅
D. Cryoprecipitated AHF
32. Cryoprecipitated AHF:
A. is indicated for fibrinogen deficiencies ✅
B. should be stored at 4oC prior to administration
C. will not transmit hepatitis B virus
D. is indicated for the treatment of hemophilia B
A. is indicated for fibrinogen deficiencies ✅
B. should be stored at 4oC prior to administration
C. will not transmit hepatitis B virus
D. is indicated for the treatment of hemophilia B
33. Which apheresis platelets product should be irradiated?
A. autologous unit collected prior to surgery
B. random stock unit going to a patient with DIC
C. a directed donation given by a mother for her son ✅
D. a directed donation given by an unrelated family friend
A. autologous unit collected prior to surgery
B. random stock unit going to a patient with DIC
C. a directed donation given by a mother for her son ✅
D. a directed donation given by an unrelated family friend
34. Irradiation of a unit of Red Blood Cells is done to prevent the replication of donor:
A. granulocytes
B. lymphocytes ✅
C. red cells
D. platelets
A. granulocytes
B. lymphocytes ✅
C. red cells
D. platelets
35. Plastic bag overwraps are recommended when thawing units of FFP in 37oC water baths because they prevent:
A. the FFP bag from cracking when it contacts the warm water
B. water from slowly dialyzing across the bag membrane
C. the entry ports from becoming contaminated with water
D. the label from peeling off as the water circulates in the bath ✅
A. the FFP bag from cracking when it contacts the warm water
B. water from slowly dialyzing across the bag membrane
C. the entry ports from becoming contaminated with water
D. the label from peeling off as the water circulates in the bath ✅
36. Which of the following blood components must be prepared within 8 hours after phlebotomy?
A. red blood cells
B. fresh frozen plasma ✅
C. red blood cells, frozen
D. cryoprecipitated AHF
A. red blood cells
B. fresh frozen plasma ✅
C. red blood cells, frozen
D. cryoprecipitated AHF
37. Cryoprecipitated AHF contains how many units of Factor VIII?
A. 40
B. 80
C. 130
D. 250 ✅
A. 40
B. 80
C. 130
D. 250 ✅
38. Which of the following blood components contains the most Factor VIII concentration relative to volume?
A. single-donor plasma
B. cryoprecipitated AHF ✅
C. fresh frozen plasma
D. platelets
A. single-donor plasma
B. cryoprecipitated AHF ✅
C. fresh frozen plasma
D. platelets
39. The most effective component to treat a patient with fibrinogen deficiency is:
A. fresh frozen plasma
B. platelets
C. fresh whole blood
D. cryoprecipitated AHF ✅
A. fresh frozen plasma
B. platelets
C. fresh whole blood
D. cryoprecipitated AHF ✅
40. A blood component prepared by thawing fresh frozen plasma at refrigerator temperature and removing the fluid portion is:
A. plasma protein fraction
B. cryoprecipitated AHF ✅
C. factor IX complex
D. FP24
A. plasma protein fraction
B. cryoprecipitated AHF ✅
C. factor IX complex
D. FP24
41. Upon inspection, a unit of platelets is noted to have visible clots, but otherwise appears normal. The technologist should:
A. issue without concern
B. filter to remove the clots ✅
C. centrifuge to express off the clots
D. quarantine for Gram stain and culture
A. issue without concern
B. filter to remove the clots ✅
C. centrifuge to express off the clots
D. quarantine for Gram stain and culture
42. According to AABB Standards, at least 90% of all apheresis platelets units tested shall contain a minimum of how many platelets?
A. 5.5 x 1010
B. 6.5 x 1010 ✅
C. 3.0 x 1011
D. 5.0 x 1011
A. 5.5 x 1010
B. 6.5 x 1010 ✅
C. 3.0 x 1011
D. 5.0 x 1011
43. According to AABB Standards, platelets prepared from whole blood shall have at least:
A. 5.5 x 1010 platelets per unit in at least 90% of the units tested
B. 6.5 x 1010 platelets per unit in at least 90% of the units tested
C. 7.5 x 1010 platelets per unit in at least 100% of the units tested ✅
D. 8.5 x 1010 platelets per unit in at least 95% of the units tested
A. 5.5 x 1010 platelets per unit in at least 90% of the units tested
B. 6.5 x 1010 platelets per unit in at least 90% of the units tested
C. 7.5 x 1010 platelets per unit in at least 100% of the units tested ✅
D. 8.5 x 1010 platelets per unit in at least 95% of the units tested
44. Which of the following is proper procedure for preparation of platelets from whole blood?
A. light spin followed by a hard spin
B. light spin followed by 2 hard spins
C. 2 light spins ✅
D. hard spin followed by a light spin
A. light spin followed by a hard spin
B. light spin followed by 2 hard spins
C. 2 light spins ✅
D. hard spin followed by a light spin
45. According to the AABB Standards, what is the minimum pH required for platelet at the end of the storage period?
A. 6.0
B. 6.2
C. 6.8
D. 7.0 ✅
A. 6.0
B. 6.2
C. 6.8
D. 7.0 ✅
46. According to the AABB Standards, platelets must be:
A. gently agitated if stored at room temperature
B. separated within 12 hours of whole blood collection ✅
C. suspended in sufficient plasma to maintain a pH of 5.0 or lower
D. prepared only from whole blood units that have been stored at 4oC for 6 hours
A. gently agitated if stored at room temperature
B. separated within 12 hours of whole blood collection ✅
C. suspended in sufficient plasma to maintain a pH of 5.0 or lower
D. prepared only from whole blood units that have been stored at 4oC for 6 hours
47. A unit of whole blood-derived (random donor) platelets should contain at least;
A. 1.0 x 1010platelets
B. 5.5 x 1010platelets ✅
C. 5.5 x 1011platelets
D. 90% of the platelets from the original unit of whole blood
A. 1.0 x 1010platelets
B. 5.5 x 1010platelets ✅
C. 5.5 x 1011platelets
D. 90% of the platelets from the original unit of whole blood
48. Platelets prepared by apheresis should contain at least:
A. 1 x 1010platelets
B. 3 x 1010platelets
C. 3 x 1011platelets ✅
D. 5 x 1011platelets
A. 1 x 1010platelets
B. 3 x 1010platelets
C. 3 x 1011platelets ✅
D. 5 x 1011platelets
49. Leukocyte-reduced red blood cells are ordered for a newly diagnosed bone marrow candidate. What is the best way to prepare this product?
A. crossmatch only CMV-seronegative units
B. irradiate the unit with 1,500 rads
C. wash the unit the saline prior to infusion
D. transfuse through a Log3 leukocyte-removing filter ✅
A. crossmatch only CMV-seronegative units
B. irradiate the unit with 1,500 rads
C. wash the unit the saline prior to infusion
D. transfuse through a Log3 leukocyte-removing filter ✅
50. Of the following blood components, which one should be used to prevent HLA alloimmunization of the recipient?
A. red blood cells
B. granulocytes
C. irradiated red blood cells
D. leukocyte-reduced red blood cells ✅
A. red blood cells
B. granulocytes
C. irradiated red blood cells
D. leukocyte-reduced red blood cells ✅
