Chronic Lymphocytic Leukemia, Myeloproliferative Disorders, and Multiple Myeloma MCQs
- Chronic lymphocytic leukemia is characterized by all of the following except:
- A. Leukocytosis
- B. Lymphocytosis
- C. Marked shift to the left ✅
- D. Splenomegaly
- Diagnosis of chronic lymphocytic leukemia is essentially based on presence of:
- A. Lymph node enlargement
- B. Anemia
- C. Persistent lymphocytosis with characteristic immunophenotypic findings ✅
- D. Thrombocytopenia
- E. Leukocytosis
- In chronic lymphocytic leukemia, which of the following can be found:
- A. Persistent lymphocytosis
- B. Thrombocytopenia
- C. Autoimmune hemolytic anemia
- D. Lymph node enlargement
- E. All of the above ✅
- Philadelphia chromosome is present in:
- A. AML
- B. CML ✅
- C. CLL
- D. Eosinophilic leukemia
- Myeloproliferative disorders include all of the following except:
- A. Chronic myeloid leukemia
- B. Essential thrombocythaemia
- C. Prolymphocytic leukemia ✅
- D. Polycythemia rubra vera
- Regarding the diagnostic triad of multiple myeloma all are correct except:
- A. Monoclonal gammopathy
- B. Malignant plasma cell infiltration of peripheral blood ✅
- C. Osteolytic bone lesions
- D. Malignant plasma cell infiltration in bone marrow
- Multiple myeloma is characterized by:
- A. Osteolytic lesions
- B. Normal serum protein level
- C. No bone affection
- D. Lymphocyte cell infiltration in bone marrow
- E. Polyclonal gammopathy ✅
- Regarding total proteins in multiple myeloma:
- A. No change in their level
- B. Marked decrease in their level
- C. Increase in their level ✅
- D. Increase only in albumin with decrease in others
- E. Decrease in albumin
- Regarding immunoglobulins in multiple myeloma:
- A. All immunoglobulins are increased
- B. All immunoglobulins are decreased
- C. Increase of IgG and IgM and decreased other types
- D. Increase of IgM and decreased all other types
- E. Increase of one type and decreased all other types ✅
- The following is mostly present in multiple myeloma:
- A. Polyclonal gammopathy
- B. Monoclonal gammopathy ✅
- C. Polyclonal gammopathy and Monoclonal gammopathy
- D. Increase serum albumin
- E. Decreased serum calcium
- All of the following can be found in multiple myeloma except:
- A. Osteolytic lesions✅
- B. Bone marrow infiltrations by plasma cells
- C. High serum proteins with high globulins
- D. Polyclonal Ig in blood or urine or both
- E. High serum calcium
- Bone marrow examination in all of the following except:
- A. Aplastic anemia
- B. Megaloblastic anemia
- C. G6PD deficiency ✅
- D. Lipid storage disease
- E. Hypersplenism
- All these conditions are associated with splenomegaly except:
- A. Infectious mononucleosis
- B. Leukemia
- C. Lymphoma
- D. Hairy cell leukemia
- E. Sickle cell anemia ✅
- In hypersplenism, the most likely finding in the peripheral blood is:
- A. Normochromic normocytic anemia
- B. Thrombocytosis
- C. Pancytopenia ✅
- D. Lymphopenia
- E. All of the above
