Leukemia mcq - Asian Paramedics

21. Neutrophil alkaline phosphatase score is diagnostic in:

A. Chronic lymphocytic leukemia✅
B. Acute lymphoblastic leukemia
C. Acute myeloid leukemia
D. Chronic myeloid leukemia
E. All of the above

22. Neutrophil alkaline phosphatase score is elevated in all of the following disorders except:

A. Pregnancy
B. Severe infection
C. Chronic myeloid leukemia ✅
D. Polycythemia rubra vera
E. Severe aplastic anemia

23. Neutrophil alkaline phosphatase score is low in:

A. Pyogenic infection
B. Polycythemia
C. Chronic myeloid leukemia ✅
D. Acute myeloid leukemia
E. None of the above

24. Chronic myeloid leukemia is characterized by:

A. Splenomegaly
B. Marked leukocytosis
C. Myelocyte bulge
D. Basophilia
E. All of the above ✅

25. Neutrophil alkaline phosphatase is an enzyme present in the granules of:

A. Monocytes
B. Neutrophils ✅
C. Basophils
D. Lymphocytes
E. Eosinophils

26. Classical chronic myeloid leukemia is characterized by all of the following except:

A. Hypercellular BM
B. Marked shift to the left
C. Monocytosis ✅
D. Increased bone marrow megakaryocytes
E. Low Neutrophil alkaline phosphatase (NAP) score

27. In the chronic phase of chronic myeloid leukemia, all of the following are present except:

A. Philadelphia chromosome
B. Splenomegaly
C. Blast cells are more than 20% in bone marrow ✅
D. High total leucocytic count
E. Thrombocytosis

28. Diagnosis of chronic myeloid leukemia is based on all of the following except:

A. Complete blood picture
B. Bone marrow examination
C. NAP score
D. Cytogenic analysis
E. Myeloperoxidase stain ✅

29. Myeloperoxidase reaction is mostly diagnostic in:

A. Chronic myeloid leukemia
B. Acute myeloid leukemia ✅
C. Chronic lymphocytic leukemia
D. Acute lymphoblastic leukemia
E. All of the above

30. The characteristic cytogenetic abnormality in chronic myeloid leukemia is:

A. t(8,21)
B. t(9,22) ✅
C. t(15,17)
D. t(12,21)
E. t(8,14)

31. Persistent lymphocytosis with the presence of smear cells in peripheral blood is present in cases of:

A. Chronic myeloid leukemia
B. Acute lymphoblastic leukemia L1
C. Chronic lymphocytic leukemia ✅
D. Acute lymphoblastic leukemia L2
E. All of the above

32. In chronic lymphocytic leukemia, all of the following can be found except:

A. Splenomegaly
B. Lymphocytosis
C. Lymphoblasts in peripheral blood ✅
D. Lymphadenopathy

33. Chronic lymphocytic leukemia is a disease of:

A. Old age only
B. Middle age female
C. Children only
D. Elder female
E. Middle and old age ✅

34. Patients of chronic lymphocytic leukemia commonly present with:

A. DIC
B. Persistent lymphocytosis✅
C. Autoimmune hemolytic anemia
D. Thrombocytopenia and anemia
E. Splenomegaly

35. Diagnosis of chronic lymphocytic leukemia is based on the presence of:

A. Peripheral lymphocytosis with normal marrow
B. Lymphocytes > 30% in marrow with persistent lymphocytosis in blood ✅
C. Leucopenia with relative lymphocytosis
D. Atypical lymphocytosis
E. None of the above

36. In chronic myeloid leukemia (chronic phase), one criterion of the following can be found:

A. Thrombocytopenia
B. Leucopenia
C. High neutrophil alkaline phosphatase
D. Thrombocytosis ✅
E. Lymphocytosis

37. In chronic myeloid leukemia, all of the following are correct except:

A. Marked shift to the left
B. Eosinophilia and basophilia
C. Lymphocytosis ✅
D. Philadelphia chromosome positive
E. Low NAP score

38. Which of the following is the most helpful to differentiate between leukemoid reaction and chronic myeloid leukemia:

A. WBCs count
B. Immature cells
C. Platelet count
D. NAP score ✅
E. RDW

39. Lymphocytosis is one of the findings in:

A. Acute myeloid leukemia
B. Chronic myeloid leukemia
C. Acute lymphoblastic leukemia
D. Chronic lymphocytic leukemia ✅

40. All of the following can be found in peripheral blood in chronic lymphocytic leukemia except:

A. 90% lymphocytes
B. Smear cells
C. Leukocytosis
D. Stab cells (Band forms) ✅
E. Anemia

Pages: 1 2 3