DHA Exam Questions for Lab Technician
- Laboratory Studies: Red Cell Indices: Determination of relative size of RBC. 82-98 fl
- a. MCH
- b. MCV ✅
- c. MCHC
- d. HCT
- Laboratory Studies: Red Cell Indices: Measurement of average weight of Hb/RBC. 27-33 pg
- a. HCT
- b. MCV
- c. MCH ✅
- d. MCHC
- Laboratory Studies: Red Cell Indices: Evaluation of RBC saturation with Hb. 32-36%
- a. HCT
- b. MCV
- c. MCH
- d. MCHC ✅
- There are 3 classifications of Anemia. What are they?
- a. Inadequate production of Hb ✅
- b. Decreased RBC production
- c. Increased Erythrocyte destruction
- d. Blood loss
- Vitamin B12 and folic acid have similar adverse effects, but what separates one from the other?
- a. Glossitis
- b. No neurological symptoms in folic acid ✅
- c. Muscle wasting
- d. Dizziness
- Folic acid therapy can cause sickle cell anemia
- a. True
- b. False ✅
- c. Equal
- d. All are above
- Both vitamin B12 and iron have drug interactions with which of the following drugs?
- a. PPI, H2 blockers ✅
- b. Methyldopa
- c. Metformin
- Hydroxyurea increases hemoglobin production and decreases reticulocyte cells.
- a. True ✅
- b. False
- Hydroxyurea:
- a. Decreases nitric oxide
- b. Increases neutrophil and monocytes
- c. Inhibits DNA synthesis by acting as a ribonucleotide ✅
- d. Reductase inhibitor
- Hydroxyurea increases the serum uric acid levels.
- a. True ✅
- b. False
- Decitabine increases the fetal hemoglobin production by inducing methylation of DNA and thus prevents the switch from gamma to beta-globin production.
- a. True
- b. False ✅
- Hypocupremia is seen in
- a. Osteoporosis, nephrotic disease
- b. Sprue, celiac disease
- c. Cardiovascular disease, colon cancer
- d. All of the above ✅
- Wilson’s disease can cause liver problems
- a. True ✅
- b. False
- What are the treatment options for Wilson’s disease?
- a. Pencillamine
- b. Trientine
- c. Potassium disulfide
- d. Zinc
- e. All of Above ✅
- Aplasia can occur because of riboflavin deficiency?
- a. True ✅
- b. False
- Angular stomatitis/cheilosis is a symptom of vitamin B12 deficiency?
- a. True
- b. False ✅
- Antimalarial drugs and high-dose birth control will increase riboflavin.
- a. True
- b. False ✅
- Which test can be used to detect hemolytic anemia?
- a. Coombs test ✅
- b. Genetic testing
- c. Peripheral blood smear (PBS)
- d. Schilling test
- Which anemia is classified as not being able to use iron properly to synthesize hemoglobin because of an inherited cause.
- a. Iron deficiency anemia
- b. Hypochromic anemia ✅
- c. Aplastic anemia
- Aplastic anemia can be induced by drugs such as Lithium, acetazolamide, and aspirin
- a. True ✅
- b. False
- This fatal disorder results from clot/thrombus formation in the blood circulation
- a. Thromboembolism
- b. DVT
- c. PAD
- d. Pulmonary embolism
- e. All of the above ✅
- Homan’s sign is classified as pain behind the knee
- a. True ✅
- b. False
- Patients that are sensitive to aspirin can take:
- a. Sulfinpyrazone
- b. Clopidogrel
- c. Ticlopidine
- d. All of Above ✅
- What is the life span of RBC
- a. 200
- b. 120 ✅
- c. 100
- d. 80
- This drug can potentiate the effect of prostacyclins to antagonize platelet stickiness and therefore decreases platelet adhesion to thrombogenic surfaces.
- a. Sulfinpyrazone
- b. Dipyridamole ✅
- c. Ticlopidine
- Which drug can be given as a prophylaxis for cardiovascular effects?
- a. Ticlopidine
- b. Clopidogrel ✅
- c. Dipyridamol ✅
- Which drug can increase intracellular levels of cAMP by inhibiting cyclic nucleotide phosphodiesterase?
- a. Sildenafil ✅
- b. Ticlopidine
- c. Clopidogrel
- d. Dipyridamol ✅
- Warfarin should be used with caution in the following:
- a. Alcoholic liver disease
- b. Gastrointestinal bleeding
- c. Recent neurosurgery
- d. Liver impairment ✅
- Isozymes of 2C can greatly affect warfarin
- a. True ✅
- b. False
- Absolute lymphocytosis (>5000/mm^3) without adenopathy, hepatosplenomegaly, anemia, thrombocytopenia is what stage in CLL prognosis Scoring-Rai Staging System?
- a. Stage 0 ✅
- b. Stage I
- c. Stage II
- d. Stage III
- e. Stage IV
- Conventional treatment is ______ for Rai stage II
- a. Antibiotics
- b. Chemotherapy ✅
- c. Antivirals
- d. Rest
- In patients with low numbers of neoplastic cells, sometimes due to treatment, PCR to amplify DNA can improve sensitivity and detect signs of relapse.
- a. True ✅
- b. False
- Chronic lymphocytic leukemia is most common in what kind of people?
- a. Young adults
- b. Older adults ✅
- Absolute lymphocytosis and thrombocytopenia (< 100,000/mm^3) with or without lymphadenopathy, hepatomegaly, splenomegaly, or anemia is what stage in CLL prognosis Scoring-Rai Staging System?
- a. Stage 0
- b. Stage I
- c. Stage II
- d. Stage III
- e. Stage IV ✅
- Chronic Lymphocytic Leukemia is characterized by peripheral blood and bone marrow _____.
- a. Lymphocytopenia
- b. Lymphocytosis ✅
- Chronic Lymphocytic Leukemia is characterized by gradual accumulation of small mature ______ cells.
- a. T
- b. B ✅
- c. NK
- Which of the following is the most mature normoblast?
- a. Orthochromic Normoblast ✅
- b. Basophilic Normoblast
- c. Pronormoblast
- d. Polychromatic Normoblast
- Absolute lymphocytosis with either hepatomegaly or splenomegaly with or without lymphadenopathy is what stage in CLL prognosis Scoring-Rai Staging System?
- a. Stage 0
- b. Stage I
- c. Stage II ✅
- d. Stage III
- e. Stage IV
- Absolute lymphocytosis without lymphadenopathy without hepatosplenomegaly, anemia, or thrombocytopenia is what stage in CLL prognosis Scoring-Rai Staging System?
- a. Stage 0
- b. Stage I ✅
- c. Stage II
- d. Stage III
- e. Stage IV
- In Chronic Lymphocytic Leukemia, the Lymphocyte appearance: small or slightly larger than normal, hypercondensed (almost ________ appearing) nuclear chromatin pattern, bare nuclei called “smudge cells” are common.
- a. Soccer-ball ✅
- b. Basketball
- c. Football
- d. Tennis-ball
- Which of the following forms of Hb molecule has the lowest affinity for oxygen?
- a. Tense ✅
- b. Relaxed
- c. Arterial
- d. Venous
- What is the recommended cleaner for removing all oil from the objective lens?
- a. 70% alcohol or lens cleaner ✅
- b. Xylene
- c. Water
- d. Benzene
- Intravascular hemolysis is the result of trauma to RBCs while in the circulation
- a. True ✅
- b. False
- A 1:20 dilution was made in a Unopette, with glacial acetic acid as the diluent. The four corner squares on BOTH sides of the hemacytometer are counted for a total of 100 cells. What is the total WBC (x10^9/L.?
- a. 0.25
- b. 2.5 ✅
- c. 5
- d. 10
- The shape of a cell is maintained by which of the following?
- a. Microtubules ✅
- b. Spindle Fibers
- c. Ribosomes
- d. Centrioles
- At which month of fetal development does the bone marrow become the primary site of hematopoiesis?
- a. 2nd
- b. 5th
- c. End of 6th month ✅
- d. End of 7th month
- Which types of cells develop from yolk sacs (Mesoblastic phase)?
- a. Hb F, Hg A2, and Hg A
- b. Gower 1 and Gower 2 Hgb
- c. Portland Hgb
- d. Only Erythroblasts ✅
- Normal Adult Hb A contains the following polypeptide chains:
- a. Alpha and beta ✅
- b. Alpha and epsilon
- c. Alpha and delta
- d. Alpha and brotherton
- Allergic reactions are frequently associated with an increase in the presence of:
- a. Lymphocytes
- b. Neutrophils
- c. Monocytes
- d. Eosinophils ✅
- Lipid exchange between the RBC membrane and the plasma occurs:
- a. To replace lost lipids in the membrane ✅
- b. To provide a mechanism for excretion of lipid-soluble RBC waste products
- c. To ensure symmetry between the composition of the interior and exterior lipid layers
- d. To provide lipid-soluble nutrients to the RBC
