Quiz Answers

Quiz Answers

  1. A donor will not be considered as permanent deferred if donor have?
    • a. HIV Positive
    • b. Hepatitis A ✅
    • c. Hepatitis B
    • d. Hepatitis C
  2. Antisera A Color is __ and Antisera B color is __?
    • a. Blue and Yellow ✅
    • b. Yellow and Blue
    • c. Blue and Red
    • d. Yellow and Red
  3. Most fetal incompatibility causing?
    • a. Iron deficiency Anemia
    • b. Macrocytic anemia
    • c. Leukemia
    • d. Hemolytic Disease of newborn ✅
  4. Which of the following is present in Cryoprecipitate?
    • a. Factor XI
    • b. Factor V
    • c. Factor X
    • d. Factor VIII ✅
  5. Which immunoglobulin is involved in the delayed hemolytic reaction?
    • a. IgG ✅
    • b. IgM
    • c. IgD
    • d. IgE
  6. The D antigen is present in?
    • a. Platelets
    • b. RBCs ✅
    • c. WBCs
    • d. None of these
  7. What are the hepatitis viruses screened in donor blood?
    • a. A and B
    • b. B and C ✅
    • c. A and C
    • d. A, B and C
  8. ___ cannot be a reason for transfusion reaction?
    • a. Hemolyzed Blood
    • b. Compatible Blood ✅
    • c. Mismatched blood
    • d. Infected blood
  9. Thiamine is vitamin
    • a. B1 ✅
    • b. B2
    • c. B6
    • d. B12
  10. The iron stored in intestinal mucosal cells is complexed to
    • a. Ferritin ✅
    • b. Intrinsic factor
    • c. Oprelvekin
    • d. Transcobalamin II
    • e. Transferrin
  11. Which of the following is most likely to be required by a 5-year-old boy with chronic renal insufficiency?
    • a. Erythropoietin ✅
    • b. G-CSF
    • c. Interleukin – 11
    • d. Stem cell factor
    • e. Thrombopoietin
  12. In adults, approximately ______ mg of thiamine per day is completely degraded by the tissue
    • a. 0.01
    • b. 0.1
    • c. 1.0 ✅
    • d. 10.0
  13. The drug of choice for the management of osteoporosis caused by high-dose use of glucocorticoids is
    • a. Alendronate ✅
    • b. Calcitonin
    • c. Mestranol
    • d. Oxandrolone
    • e. Vitamin D
  14. Which of the following drugs is correctly associated with its clinical application?
    • a. Erythropoietin : Macrocytic anemia
    • b. Filgrastim : Thrombocytopenia due to myelocytic leukemia
    • c. Iron dextran : Severe macrocytic anemia
    • d. Ferrous sulfate : Microcytic anemia of pregnancy ✅
    • e. Folic acid : Hemochromatosis
  15. Conversion of methionine to cysteine depends on vitamin
    • a. B1
    • b. B2
    • c. B6 ✅
    • d. B12
  16. Avidin, a protein found in egg white, is an antagonist of
    • a. Biotin ✅
    • b. Pantothenic acid
    • c. Choline
    • d. Pyridoxal
  17. All of the following are important functions of magnesium (Mg) except
    • a. Nerve conduction
    • b. Phospholipid synthesis ✅
    • c. Muscle contractility
    • d. Carbohydrate, fat, and electrolyte metabolism
  18. Factors likely to cause an increase in the blood urea nitrogen (BUN) level include
    • a. Intramuscular (IM) injection of diazepam (Valium)
    • b. Severe liver disease
    • c. Chronic kidney disease ✅
  19. Physiologically, carnitine plays the following role
    • a. Important for oxidation of fatty acids ✅
    • b. Decreases aerobic metabolism of carbohydrates
    • c. Decreases rate of oxidative phosphorylation
    • d. All of the above
  20. Patients receiving iron therapy should be warned about
    • a. Dizziness
    • b. Ringing in the ears
    • c. Danger of sunlight
    • d. Blackening of the stool ✅
    • e. Paresthesia
  21. Therapeutically, vitamin B1 has been employed most successfully in the treatment of
    • a. Microcytic anemia
    • b. Pellagra
    • c. Scurvy
    • d. Beriberi ✅
    • e. Macrocytic anemia
  22. Magnesium ion is necessary in
    • a. Stimulating enzyme systems
    • b. Muscular contraction
    • c. Nerve conduction
    • d. All of the above ✅
    • e. None of the above
  23. The following derivatives of retinal show the greatest biological potency than others
    • a. 9-Cis-retinoic acid
    • b. All-trans-retinoic acid
    • c. All-trans-retinol ✅
    • d. 11-Cis-retinal
  24. The drug used for controlling tetany is
    • a. Intravenous diazepam
    • b. Intramuscular vitamin D
    • c. Intravenous calcium gluconate ✅
    • d. Intravenous calcitonin
  25. Absorption of oral iron preparations can be facilitated by coadministering
    • a. Antacids
    • b. Tetracyclines
    • c. Phosphates
    • d. Ascorbic acid ✅
  26. The gut controls the entry of ingested iron in the body by
    • a. Regulating the availability of apoferritin which acts as the carrier of iron across the mucosal cell
    • b. Regulating the turnover of apoferritin-ferritin interconversion in the mucosal cell
    • c. Complexing excess iron to form ferritin which remains stored in the mucosal cell and is shed off ✅
    • d. Regulating the number of transferring receptors on the mucosal cell
  27. The percentage of elemental iron in hydrated ferrous sulfate is
    • a. 5%
    • b. 10%
    • c. 20% ✅
    • d. 33%
  28. In isolated fibroblast or epithelial cells, retinoids enhance the synthesis of the following protein
    • a. Fibronectin ✅
    • b. Collagenase
    • c. Certain species of keratin
    • d. All of the above
  29. The side effect which primarily limits acceptability of oral iron therapy is
    • a. Epigastric pain and bowel upset ✅
    • b. Black stools
    • c. Staining of teeth
    • d. Metallic taste
  30. Iron sorbitol-citric acid differs from iron dextran in that
    • a. It cannot be injected i.v. ✅
    • b. It is not excreted in urine
    • c. It is not bound to transferritin in plasma
    • d. It produces fewer side effects
  31. Which of the following is true about iron therapy?
    • a. Haemoglobin response to intramuscular iron is faster than with oral iron therapy
    • b. Iron must be given orally except in pernicious anaemia
    • c. Prophylactic iron therapy must be given during pregnancy ✅
    • d. Infants on breast feeding do not require medicinal iron
  32. Concentrations of retinal in plasma in excess of _____ μg/dl usually are diagnostic of hypervitaminosis A
    • a. 10
    • b. 50
    • c. 100 ✅
    • d. 200
  33. Megaloblastic anaemia occurs in
    • a. Vitamin B12 but not folic acid deficiency
    • b. Folic acid but not Vitamin B12 deficiency
    • c. Either Vitamin B12 or folic acid deficiency ✅
    • d. Only combined Vitamin B12 + folic acid deficiency
  34. The daily dietary requirement of Vitamin B12 by an adult is
    • a. 1-3 μg ✅
    • b. 50-100 μg
    • c. 0.1-0.5 μg
    • d. 5-10 μg
  35. Which of the following factor(s) is/are required for the absorption of Vitamin B12 ingested in physiological amounts?
    • a. Gastric acid
    • b. Gastric intrinsic factor
    • c. Transcobalamine
    • d. Both (a) and (b) ✅
  36. Hydroxocobalamine differs from cyanocobalamine in that
    • a. It is more protein bound and better retained
    • b. It is beneficial in tobacco amblyopia
    • c. It benefits haematological but not neurological manifestations of Vit B12 deficiency
    • d. Both (a) and (b) ✅
  37. Megaloblastic anemia is caused by deficiency of
    • a. Iron
    • b. Vitamin B12 ✅
    • c. Vitamin C
    • d. All of the above
  38. Vitamin B12 is a required co-factor for the following reaction
    • a. Conversion of methylmalonyl-CoA to succinyl-CoA
    • b. Conversion of 5-CH3-H4-folate to H4-folate
    • c. Conversion of homocysteine to methionine
    • d. All of the above ✅
  39. Vitamin K is indicated for the treatment of bleeding occurring in patients
    • a. Being treated with heparin
    • b. Being treated with streptokinase
    • c. Of obstructive jaundice ✅
    • d. Of peptic ulcer
  40. Menadione (Vitamin K3)
    • a. Can cause hemolysis in patients with G-6-PD deficiency ✅
    • b. Is given in large doses in patients with severe liver disease
    • c. Is useful to prevent haemorrhagic disease of the newborn
    • d. Is the preparation of choice to antagonize the effect of warfarin overdose
  41. Vitamin K promotes the hepatic biosynthesis of the following blood clotting factor
    • a. Factor I
    • b. Factor II ✅
    • c. Factor VIII
    • d. All of the above
  42. Folinic acid is principally used
    • a. In pernicious anaemia
    • b. In megaloblastic anaemia secondary to Vitamin B12
    • c. Along with methotrexate therapy ✅
    • d. In treatment of folic acid deficiency
  43. Penicillamine
    • a. Is effective orally ✅
    • b. Can cause anaphylactic reactions in patients allergic to penicillin
    • c. Is safe in pregnancy
    • d. Is not effective in lead poisoning
  44. Succimer
    • a. Can significantly mobilize essential metals
    • b. Produces less toxicity than Dimercaprol ✅
    • c. Is ineffective orally
    • d. Is contraindicated in children
  45. Causes spurious decrease in MCV
    • a. Cryofibrinogen ✅
    • b. Hyperglycemia
    • c. Autoagglutination
    • d. High WBC ct
    • e. Reduced red cell deformability
  46. When the entire CBC is suppressed due to either anemia, infection, or hemorrhage is called?
    • a. Erythroplasia
    • b. Thrombocytopenia
    • c. Pancytopenia ✅
    • d. Leukopenia
  47. Total RBC count for Women is?
    • a. 4.4 -6
    • b. 4.2-5
    • c. 4.0-5.0 ✅
    • d. 4.2-5.2
  48. Total RBC for men?
    • a. 4.0-5.0
    • b. 4.6-6.0 ✅
    • c. 4.2-6.5
    • d. 4.0-6.0
  49. What is the major metabolically available storage form of iron in the body?
    • a. Hemosiderin
    • b. Ferritin ✅
    • c. Transferrin
    • d. Hemoglobin
  50. The best source of active bone marrow from a 20-year-old would be:
    • a. Iliac Crest (hip) ✅
    • b. Femur (thigh)
    • c. Distal radius (forearm)
    • d. Tibia (shin)
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