Quiz Answers
- A donor will not be considered as permanent deferred if donor have?
- a. HIV Positive
- b. Hepatitis A ✅
- c. Hepatitis B
- d. Hepatitis C
- Antisera A Color is __ and Antisera B color is __?
- a. Blue and Yellow ✅
- b. Yellow and Blue
- c. Blue and Red
- d. Yellow and Red
- Most fetal incompatibility causing?
- a. Iron deficiency Anemia
- b. Macrocytic anemia
- c. Leukemia
- d. Hemolytic Disease of newborn ✅
- Which of the following is present in Cryoprecipitate?
- a. Factor XI
- b. Factor V
- c. Factor X
- d. Factor VIII ✅
- Which immunoglobulin is involved in the delayed hemolytic reaction?
- a. IgG ✅
- b. IgM
- c. IgD
- d. IgE
- The D antigen is present in?
- a. Platelets
- b. RBCs ✅
- c. WBCs
- d. None of these
- What are the hepatitis viruses screened in donor blood?
- a. A and B
- b. B and C ✅
- c. A and C
- d. A, B and C
- ___ cannot be a reason for transfusion reaction?
- a. Hemolyzed Blood
- b. Compatible Blood ✅
- c. Mismatched blood
- d. Infected blood
- Thiamine is vitamin
- a. B1 ✅
- b. B2
- c. B6
- d. B12
- The iron stored in intestinal mucosal cells is complexed to
- a. Ferritin ✅
- b. Intrinsic factor
- c. Oprelvekin
- d. Transcobalamin II
- e. Transferrin
- Which of the following is most likely to be required by a 5-year-old boy with chronic renal insufficiency?
- a. Erythropoietin ✅
- b. G-CSF
- c. Interleukin – 11
- d. Stem cell factor
- e. Thrombopoietin
- In adults, approximately ______ mg of thiamine per day is completely degraded by the tissue
- a. 0.01
- b. 0.1
- c. 1.0 ✅
- d. 10.0
- The drug of choice for the management of osteoporosis caused by high-dose use of glucocorticoids is
- a. Alendronate ✅
- b. Calcitonin
- c. Mestranol
- d. Oxandrolone
- e. Vitamin D
- Which of the following drugs is correctly associated with its clinical application?
- a. Erythropoietin : Macrocytic anemia
- b. Filgrastim : Thrombocytopenia due to myelocytic leukemia
- c. Iron dextran : Severe macrocytic anemia
- d. Ferrous sulfate : Microcytic anemia of pregnancy ✅
- e. Folic acid : Hemochromatosis
- Conversion of methionine to cysteine depends on vitamin
- a. B1
- b. B2
- c. B6 ✅
- d. B12
- Avidin, a protein found in egg white, is an antagonist of
- a. Biotin ✅
- b. Pantothenic acid
- c. Choline
- d. Pyridoxal
- All of the following are important functions of magnesium (Mg) except
- a. Nerve conduction
- b. Phospholipid synthesis ✅
- c. Muscle contractility
- d. Carbohydrate, fat, and electrolyte metabolism
- Factors likely to cause an increase in the blood urea nitrogen (BUN) level include
- a. Intramuscular (IM) injection of diazepam (Valium)
- b. Severe liver disease
- c. Chronic kidney disease ✅
- Physiologically, carnitine plays the following role
- a. Important for oxidation of fatty acids ✅
- b. Decreases aerobic metabolism of carbohydrates
- c. Decreases rate of oxidative phosphorylation
- d. All of the above
- Patients receiving iron therapy should be warned about
- a. Dizziness
- b. Ringing in the ears
- c. Danger of sunlight
- d. Blackening of the stool ✅
- e. Paresthesia
- Therapeutically, vitamin B1 has been employed most successfully in the treatment of
- a. Microcytic anemia
- b. Pellagra
- c. Scurvy
- d. Beriberi ✅
- e. Macrocytic anemia
- Magnesium ion is necessary in
- a. Stimulating enzyme systems
- b. Muscular contraction
- c. Nerve conduction
- d. All of the above ✅
- e. None of the above
- The following derivatives of retinal show the greatest biological potency than others
- a. 9-Cis-retinoic acid
- b. All-trans-retinoic acid
- c. All-trans-retinol ✅
- d. 11-Cis-retinal
- The drug used for controlling tetany is
- a. Intravenous diazepam
- b. Intramuscular vitamin D
- c. Intravenous calcium gluconate ✅
- d. Intravenous calcitonin
- Absorption of oral iron preparations can be facilitated by coadministering
- a. Antacids
- b. Tetracyclines
- c. Phosphates
- d. Ascorbic acid ✅
- The gut controls the entry of ingested iron in the body by
- a. Regulating the availability of apoferritin which acts as the carrier of iron across the mucosal cell
- b. Regulating the turnover of apoferritin-ferritin interconversion in the mucosal cell
- c. Complexing excess iron to form ferritin which remains stored in the mucosal cell and is shed off ✅
- d. Regulating the number of transferring receptors on the mucosal cell
- The percentage of elemental iron in hydrated ferrous sulfate is
- a. 5%
- b. 10%
- c. 20% ✅
- d. 33%
- In isolated fibroblast or epithelial cells, retinoids enhance the synthesis of the following protein
- a. Fibronectin ✅
- b. Collagenase
- c. Certain species of keratin
- d. All of the above
- The side effect which primarily limits acceptability of oral iron therapy is
- a. Epigastric pain and bowel upset ✅
- b. Black stools
- c. Staining of teeth
- d. Metallic taste
- Iron sorbitol-citric acid differs from iron dextran in that
- a. It cannot be injected i.v. ✅
- b. It is not excreted in urine
- c. It is not bound to transferritin in plasma
- d. It produces fewer side effects
- Which of the following is true about iron therapy?
- a. Haemoglobin response to intramuscular iron is faster than with oral iron therapy
- b. Iron must be given orally except in pernicious anaemia
- c. Prophylactic iron therapy must be given during pregnancy ✅
- d. Infants on breast feeding do not require medicinal iron
- Concentrations of retinal in plasma in excess of _____ μg/dl usually are diagnostic of hypervitaminosis A
- a. 10
- b. 50
- c. 100 ✅
- d. 200
- Megaloblastic anaemia occurs in
- a. Vitamin B12 but not folic acid deficiency
- b. Folic acid but not Vitamin B12 deficiency
- c. Either Vitamin B12 or folic acid deficiency ✅
- d. Only combined Vitamin B12 + folic acid deficiency
- The daily dietary requirement of Vitamin B12 by an adult is
- a. 1-3 μg ✅
- b. 50-100 μg
- c. 0.1-0.5 μg
- d. 5-10 μg
- Which of the following factor(s) is/are required for the absorption of Vitamin B12 ingested in physiological amounts?
- a. Gastric acid
- b. Gastric intrinsic factor
- c. Transcobalamine
- d. Both (a) and (b) ✅
- Hydroxocobalamine differs from cyanocobalamine in that
- a. It is more protein bound and better retained
- b. It is beneficial in tobacco amblyopia
- c. It benefits haematological but not neurological manifestations of Vit B12 deficiency
- d. Both (a) and (b) ✅
- Megaloblastic anemia is caused by deficiency of
- a. Iron
- b. Vitamin B12 ✅
- c. Vitamin C
- d. All of the above
- Vitamin B12 is a required co-factor for the following reaction
- a. Conversion of methylmalonyl-CoA to succinyl-CoA
- b. Conversion of 5-CH3-H4-folate to H4-folate
- c. Conversion of homocysteine to methionine
- d. All of the above ✅
- Vitamin K is indicated for the treatment of bleeding occurring in patients
- a. Being treated with heparin
- b. Being treated with streptokinase
- c. Of obstructive jaundice ✅
- d. Of peptic ulcer
- Menadione (Vitamin K3)
- a. Can cause hemolysis in patients with G-6-PD deficiency ✅
- b. Is given in large doses in patients with severe liver disease
- c. Is useful to prevent haemorrhagic disease of the newborn
- d. Is the preparation of choice to antagonize the effect of warfarin overdose
- Vitamin K promotes the hepatic biosynthesis of the following blood clotting factor
- a. Factor I
- b. Factor II ✅
- c. Factor VIII
- d. All of the above
- Folinic acid is principally used
- a. In pernicious anaemia
- b. In megaloblastic anaemia secondary to Vitamin B12
- c. Along with methotrexate therapy ✅
- d. In treatment of folic acid deficiency
- Penicillamine
- a. Is effective orally ✅
- b. Can cause anaphylactic reactions in patients allergic to penicillin
- c. Is safe in pregnancy
- d. Is not effective in lead poisoning
- Succimer
- a. Can significantly mobilize essential metals
- b. Produces less toxicity than Dimercaprol ✅
- c. Is ineffective orally
- d. Is contraindicated in children
- Causes spurious decrease in MCV
- a. Cryofibrinogen ✅
- b. Hyperglycemia
- c. Autoagglutination
- d. High WBC ct
- e. Reduced red cell deformability
- When the entire CBC is suppressed due to either anemia, infection, or hemorrhage is called?
- a. Erythroplasia
- b. Thrombocytopenia
- c. Pancytopenia ✅
- d. Leukopenia
- Total RBC count for Women is?
- a. 4.4 -6
- b. 4.2-5
- c. 4.0-5.0 ✅
- d. 4.2-5.2
- Total RBC for men?
- a. 4.0-5.0
- b. 4.6-6.0 ✅
- c. 4.2-6.5
- d. 4.0-6.0
- What is the major metabolically available storage form of iron in the body?
- a. Hemosiderin
- b. Ferritin ✅
- c. Transferrin
- d. Hemoglobin
- The best source of active bone marrow from a 20-year-old would be:
- a. Iliac Crest (hip) ✅
- b. Femur (thigh)
- c. Distal radius (forearm)
- d. Tibia (shin)
