Platelet Function Studies, ITP, DIC, and Related Topics MCQs

Platelet Function Studies, ITP, DIC, and Related Topics MCQs

Platelet function study with ristocetin shows defective response in:
- A. Glanzmann’s disease
- B. Von Willebrand disease
- C. Bernard Soulier syndrome
- D. Bernard Soulier syndrome And Von Willebrand disease ✅

Platelet function study with collagen shows defective response in:
- A. Glanzmann’s disease ✅
- B. Von Willebrand disease
- C. Bernard Soulier syndrome
- D. Bernard Soulier syndrome And Von Willebrand disease

In ITP there is:
- A. Prolonged PT
- B. Prolonged PTT
- C. Decreased platelet count
- D. Increased bone marrow megakaryocytes
- E. Decreased platelet count And Increased bone marrow megakaryocytes ✅

In massive liver disease there is:
- A. Prolonged PT and PTT
- B. Thrombocytosis
- C. Thrombocytopenia
- D. Prolonged PT and PTT And Thrombocytopenia ✅
- E. Prolonged PT and PTT And Thrombocytosis

Thrombocytopenia is a common finding in:
- A. Aplastic anemia
- B. Massive liver disease
- C. ITP
- D. Hypersplenism
- E. All of the above ✅

Normal platelet count ranges from:
- A. 150 – 400 x10^9 /L ✅
- B. 150 – 400 x10^3 /L
- C. 150 – 400 x10^6 /L
- D. 150 – 400 x10^12 /L
- E. 150 – 450 x10^6 /L

All the following findings are present in DIC except:
- A. Thrombocytopenia
- B. Decreased serum FDPs level ✅
- C. Decreased serum fibrinogen level
- D. Prolonged PT
- E. Prolonged PTT

In DIC:
- A. PT and PTT are prolonged
- B. TT and BT are prolonged
- C. Platelet count and fibrinogen are decreased
- D. All of the above ✅

D-dimer assay is valuable in:
- A. ITP
- B. DIC ✅
- C. Hemophilia A
- D. Factor VII deficiency
- E. Platelet function defect

In hemophilia B there is:
- A. Prolonged PT
- B. Prolonged PTT ✅
- C. Prolonged TT
- D. Bleeding time is prolonged
- E. None of the above

In von Willebrand disease:
- A. Prolonged PT
- B. Prolonged TT
- C. Bleeding time is prolonged ✅
- D. PTT test is normal
- E. Prolonged PT & TT

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