Coagulation Tests MCQs

Coagulation Tests MCQs

  1. Prothrombin time is used to monitor:
    • A. Intravenous anticoagulant therapy
    • B. Oral anticoagulant therapy✅
    • C. A and B
    • D. Platelet function defect

  2. Prothrombin time is prolonged in:
    • A. Hemophilia A
    • B. Massive liver disease ✅
    • C. Idiopathic thrombocytopenic purpura
    • D. Bone marrow failure
    • E. Thrombocytopenia purpura

  3. Activated partial thromboplastin time is used to detect:
    • A. Extrinsic pathway defect
    • B. Intrinsic pathway defect only
    • C. Fibrinolytic pathway defect
    • D. Platelet function defect
    • E. Intrinsic & common pathway defect ✅

  4. Activated partial thromboplastin time is prolonged in:
    • A. Hemophilia B
    • B. Factor VIII deficiency
    • C. Blood vessel disease
    • D. Hemophilia B & factor VIII deficiency ✅
    • E. None of the above

  5. Heparin anticoagulant therapy is best monitored by:
    • A. Prothrombin time
    • B. Activated partial thromboplastin time ✅
    • C. Bleeding time
    • D. Thrombin time
    • E. None of the above

  6. Thrombin time measures:
    • A. Conversion of prothrombin to thrombin
    • B. Conversion of fibrinogen to fibrin ✅
    • C. Conversion of factor VII to active factor VII
    • D. Conversion of plasminogen to plasmin

  7. International normalized ratio is the best monitor for:
    • A. IV anticoagulant therapy
    • B. Oral anticoagulant therapy ✅
    • C. Platelet replacement therapy
    • D. Cryoglobulin therapy
    • E. All of the above

  8. Bleeding time is prolonged in the following conditions except:
    • A. Henoch Schonlein purpura
    • B. Bernard Soulier syndrome
    • C. Immature thrombocytopenic purpura
    • D. Disseminated intravascular coagulation
    • E. Hemophilia A ✅

  9. All of the following conditions lead to prolonged bleeding time except:
    • A. Von Willebrand disease
    • B. Thrombocytopenia
    • C. Haemophilia A ✅
    • D. Henoch Schonlein purpura
    • E. DIC

  10. Bleeding time is used clinically to screen for a significant defect in:
    • A. Coagulation defect
    • B. Platelet function ✅
    • C. Fibrinolytic pathway
    • D. None of the above
    • E. All of the above

  11. Thrombocytopenia is seen in:
    • A. Fanconi syndrome✅
    • B. Glanzmann’s disease
    • C. Von Willebrand disease
    • D. Storage pool disease
    • E. None of the above

  12. In immune thrombocytopenic purpura all of the following is correct except:
    • A. Normal PT
    • B. Prolonged bleeding time
    • C. Normal PTT
    • D. Decreased bone marrow megakaryocytes ✅
    • E. Decreased platelet life span

  13. Routine evaluation of patients with bleeding tendency necessitates:
    • A. Through history and clinical examination✅
    • B. TLC
    • C. Collagen markers assay
    • D. Trephine biopsy
    • E. All of the above

  14. Causes of vascular purpura include:
    • A. ITP
    • B. Henoch Schonlein purpura ✅
    • C. Glanzmann’s disease
    • D. Bernard Soulier syndrome

  15. Platelet adhesion defect occurs in:
    • A. Henoch Schonlein purpura
    • B. Glanzmann’s disease
    • C. Bernard Soulier syndrome ✅
    • D. All of the above
    • E. None of the above

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