Coagulation Tests MCQs
- Prothrombin time is used to monitor:
- A. Intravenous anticoagulant therapy
- B. Oral anticoagulant therapy✅
- C. A and B
- D. Platelet function defect
- Prothrombin time is prolonged in:
- A. Hemophilia A
- B. Massive liver disease ✅
- C. Idiopathic thrombocytopenic purpura
- D. Bone marrow failure
- E. Thrombocytopenia purpura
- Activated partial thromboplastin time is used to detect:
- A. Extrinsic pathway defect
- B. Intrinsic pathway defect only
- C. Fibrinolytic pathway defect
- D. Platelet function defect
- E. Intrinsic & common pathway defect ✅
- Activated partial thromboplastin time is prolonged in:
- A. Hemophilia B
- B. Factor VIII deficiency
- C. Blood vessel disease
- D. Hemophilia B & factor VIII deficiency ✅
- E. None of the above
- Heparin anticoagulant therapy is best monitored by:
- A. Prothrombin time
- B. Activated partial thromboplastin time ✅
- C. Bleeding time
- D. Thrombin time
- E. None of the above
- Thrombin time measures:
- A. Conversion of prothrombin to thrombin
- B. Conversion of fibrinogen to fibrin ✅
- C. Conversion of factor VII to active factor VII
- D. Conversion of plasminogen to plasmin
- International normalized ratio is the best monitor for:
- A. IV anticoagulant therapy
- B. Oral anticoagulant therapy ✅
- C. Platelet replacement therapy
- D. Cryoglobulin therapy
- E. All of the above
- Bleeding time is prolonged in the following conditions except:
- A. Henoch Schonlein purpura
- B. Bernard Soulier syndrome
- C. Immature thrombocytopenic purpura
- D. Disseminated intravascular coagulation
- E. Hemophilia A ✅
- All of the following conditions lead to prolonged bleeding time except:
- A. Von Willebrand disease
- B. Thrombocytopenia
- C. Haemophilia A ✅
- D. Henoch Schonlein purpura
- E. DIC
- Bleeding time is used clinically to screen for a significant defect in:
- A. Coagulation defect
- B. Platelet function ✅
- C. Fibrinolytic pathway
- D. None of the above
- E. All of the above
- Thrombocytopenia is seen in:
- A. Fanconi syndrome✅
- B. Glanzmann’s disease
- C. Von Willebrand disease
- D. Storage pool disease
- E. None of the above
- In immune thrombocytopenic purpura all of the following is correct except:
- A. Normal PT
- B. Prolonged bleeding time
- C. Normal PTT
- D. Decreased bone marrow megakaryocytes ✅
- E. Decreased platelet life span
- Routine evaluation of patients with bleeding tendency necessitates:
- A. Through history and clinical examination✅
- B. TLC
- C. Collagen markers assay
- D. Trephine biopsy
- E. All of the above
- Causes of vascular purpura include:
- A. ITP
- B. Henoch Schonlein purpura ✅
- C. Glanzmann’s disease
- D. Bernard Soulier syndrome
- Platelet adhesion defect occurs in:
- A. Henoch Schonlein purpura
- B. Glanzmann’s disease
- C. Bernard Soulier syndrome ✅
- D. All of the above
- E. None of the above
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