Hepatitis B, Hepatitis C, and Related Topics MCQs
- Detection of low titer HBcAb IgG and positive HBsAb denotes:
- A. HBV past infection with immunity to HBV ✅
- B. HBV carrier status
- C. HBV vaccination
- D. HBV acute infection
- E. HBV chronic infection
- Co-infection of HDV and HBV is diagnosed by:
- A. Positive HBsAg and HBcAb IgG
- B. Positive HDV Ab IgM and HBcAb IgM✅
- C. Positive HBsAb and positive HDV Ab IgM
- D. Negative HBs Ab and positive HDV Ab IgM
- E. None of the above
- Super infection of HDV on HBV infection is diagnosed by:
- A. Positive HDV Ab IgG and HBcAb IgG
- B. Positive HBs Ab and HDV Ab IgM
- C. Negative HBs Ag and positive HDV Ab IgM
- D. Positive HDV Ab IgM and HDV Ab IgG
- E. Positive HBc Ab IgG, HBs Ag and HDV Ab IgM ✅
- Super infection of HDV and HBV is diagnosed by:
- A. Positive HDV Ab IgM and HBc Ab IgG and negative HBsAg
- B. Positive HBs Ab and positive HDV Ab IgG
- C. Negative HBs Ag and positive HDV Ab IgM
- D. Positive HDV Ab IgG and HBcAb IgG
- E. None of the above ✅
- As regards hepatitis B, which of the following is true:
- A. Persistence of HBsAg >6 months is an indicator of chronicity ✅
- B. Serum HBcAg indicates viral replication
- C. It is transmitted through feco-oral route
- D. Positive HBcAb and +ve HBsAb denotes post vaccination
- E. HBsAb indicated viral replication
- As regards hepatitis B, which of the following is not true:
- A. Persistence of HBsAg > 6 months is an indicator of chronicity
- B. Positive HBeAg indicates viral replication
- C. Positive HBsAB indicates immunity
- D. Positive HBvAb and +ve HBsAb denotes post vaccination ✅
- E. HBcAb is the only marker in the window gap
- As regards HBc Ab, which of the following is false:
- A. It is an important serologic marker in the window gap
- B. High titer IgG despite positive HBsAb indicates persistent viral load ✅
- C. Low titer IgG with positive HBsAb indicates past infection and immunity
- D. Negative HBcAb IgG with positive HBsAb denotes post vaccination
- The most definitive diagnostic test for HCV infection is:
- A. HCV Ab IgG by ELIZA
- B. HCV Ab IgM by ELIZA
- C. Recombinant immunoblot assay (RIBA)
- D. Viral RNA by PCR ✅
- Which of the following tests is clinically significant for HCV infection:
- A. HCV Ab by ELIZA
- B. HCV Ab by RIBA
- C. HCV RNA BY PCR
- D. Serotyping and quantitation of viral load
- E. All of the above ✅
- Carrier state in viral infection means:
- A. The virus is hidden in the host cell and can’t be detected
- B. The virus is secreted by the host after clinical recovery ✅
- C. The virus does not remain in the host after recovery
- D. None-of the above
- E. All of the above
- PCR is used to detect:
- A. Viral antigen
- B. Viral particles
- C. Viral genome ✅
- D. Viral envelope
- E. None of the above
- Primary biliary cirrhosis could be differentiated from primary sclerosing cholangitis by:
- A. Increased ALP and GGT
- B. Evidence of hepatic dysfunction
- C. Increased total IgM
- D. Frequently progresses to chronic hepatitis
- E. Positive AMA ✅
- The following is true for hepatocellular carcinoma:
- A. Mild elevation of AFP occurs in primary hepatoma
- B. Mild elevation of AFP plus elevation of CEA occurs in secondary liver cancer✅
- C. Normal level of CEA with increased levels of AFP occur in colorectal cancer without hepatic malignancy
- D. All of the above
- Tumor markers for liver metastasis include:
- A. CEA ✅
- B. ALP
- C. Transaminases
- D. All of the above
- E. None of the above
