2601. Dengue virus belongs to______?

• a. Flavi virus ✅
• b. Togaviridae
• c. Reoviridae
• d. Rhabdoviridae

2602. Which of the following statement about P24 antigen of HIV is Not True ?

• a. It can be detected during the window period
• b. Free P24 antigen disappears after the appearance of IgM response to it:
• c. Virus load parallel P24 titre
• d. It remains during asymptomatic phase ✅

2603. Which of the following viruses are most likely to cross placenta and cause fetal defect ?

• a. Herpes Simplex
• b. Mumps
• c. Rubella ✅
• d. Papilloma

2604. Which of the following viruses produces both intranuclear and intracytoplasmic inclusion bodies______?

• a. Chicken pox
• b. Rabies
• c. Small pox
• d. Measles ✅

2605. Characteristic feature of retrovirus is____?

• a. Ribonuclease
• b. Reverse transcriptase ✅
• c. DNA polymerase
• d. Restriction endonuclease

2606. Dengue Hemorrhagic fever is caused by______?

• a. Virus ✅
• b. Bacteria
• c. Parasite
• d. Bacteria superadded on virus

2607. Interferon interferes with replication of virus at the time of_______?

• a. Protein synthesis ✅
• b. DNA/RNA replication
• c. When virus enters the cell
• d. Uncoating of the virus proteins capsule

2608. Which of the following microbial cell is most resistant to antiseptics & disinfectants ?

• a. Mycobacteria
• b. Spore
• c. Prions ✅
• d. Coccidia

2609. Which of the following lesions is NOT an infection from human papilloma virus ?

• a. Verruca vulgaris
• b. Focal epithelial hyperplasia
• c. Condyloma acuminatum
• d. Keratoacanthoma ✅

2610. Prions true is_____?

• a. Readily inactivated by autoclave at 121 C ✅
• b. Evokes strong immunogenic reaction
• c. Sensitive to most chemical sterilization
• d. Contains DNA/ RNA

2611. A young pregnant woman presents with fulminant hepatic failure. The most likely etiological agent is______?

• a. Hepatitis B virus
• b. Hepatitis C virus
• c. Hepatitis E virus ✅
• d. Hepatitis A virus

2612. Salivary protein, which prevents transmission of human immunodeficiency virus via saliva, is_____?

• a. Sialoperoxidase
• b. Secretory IgA
• c. Salivary leukocyte proteinase inhibitor ✅
• d. Histidine rich proteins

2613. A dentist suffered from Hepatitis B infection 3 months back. His laboratory tests are normal but he is not allowed by the medical board to do surgical practice. He is______?

• a. Inactive carrier
• b. Healthy carrier
• c. Convalescent carrier ✅
• d. Paradoxical carrier

2614. Virus is cultured in_______?

• a. Saubourd’s agar
• b. Rogosa medium
• c. Nonembryonated egg
• d. Embryonated egg ✅

2615. Kaposi’s sarcoma (KS) usually occurs when CD4 Lymphocyte counts are______?

• a. Above 600
• b. Between 1000-2000
• c. Below 200 ✅
• d. Above 2000

2616. Mark true in following ?

• a. Hanta virus pulmonary syndrome is caused by inhalation of rodent urine and faces ✅
• b. Kyanasur forest disease is caused by bite of wild animal
• c. Lyssa virus is transmitted by ticks
• d. None of the above

2617. The world German measles is applied for_____?

• a. Rubella ✅
• b. Rubeola
• c. Herpes simplex
• d. Herpetic gingivostomatitis

2618. Hepatitis A virus is best diagnosed by_______?

• a. IgM antibodies in serum ✅
• b. Isolation form stool
• c. Culture from blood
• d. Isolation from bile

2619. Which of the following is not a pox virus ?

• a. Cowpox
• b. Molluscum contagiosum
• c. Small pox
• d. Chicken pox ✅

2620. Serological study for prevalence of Hepatitis B is best done by_____?

• a. Surface antigen ✅
• b. Surface antibody
• c. Core antigen
• d. Core antibody

2621. ELISA test when compared to western blot technique is______?

• a. Less sensitive less specific
• b. More sensitive, more specific
• c. Less sensitive, more specific
• d. More sensitive, less specific ✅

2622. The virus which causes Aplastic anemia in chronic hemolytic disease is______?

• a. Adeno
• b. Hepatitis
• c. EB virus
• d. Parvo virus ✅

2623. In HIV, gp 120, envelope glycoproteins bind specifically to____?

• a. CD8 T-cells
• b. CD4 T-cells ✅
• c. B – cells
• d. NK – cells

2624. The small nonparticulate protein leading to enhanced replication of HBV as well as HIV is______?

• a. HBc Ag
• b. HBs Ag
• c. Hbe Ag
• d. HBx Ag ✅

2625. Patients with organ transplants are most frequently infected with______?

• a. Hepatitis A
• b. Hepatitis B
• c. CMV ✅
• d. EBV

2626. EBV is responsible for all except_____?

• a. Nasopharyngeal carcinoma
• b. Burkitt’s lymphoma
• c. Hepatoma ✅
• d. Infectious mononucleosis

2627. Most common tumor associated with AIDS is________?

• a. Carcinoma
• b. Kaposi’s sarcoma ✅
• c. Melanoma
• d. Ewing’s sarcoma

2628. The overall effect of HIV is to gradually impair the immune system by interference with_____?

• a. Helper T lymphocytes ✅
• b. Natural killer cells
• c. Plasma cells
• d. Macrophages

2629. Hepatitis C virus belongs to which one of the following virus groups ?

• a. Picorna viruses
• b. Herpes viruses
• c. Hepadana viruses
• d. Flavi viruses ✅

2630. Viruses can be isolated from clinical samples by cultivation in the following except_______?

• a. Tissue culture
• b. Embryonated eggs
• c. Animals
• d. Chemically defined media ✅

2631. During the Window period of patient with AIDS_______?

• a. ELISA IS – ve
• b. Western Blot is – ve
• c. Both are – ve ✅
• d. PCR is – ve

2632. Plaque test is used routinely in virology labs for______?

• a. Identification of viral disease ✅
• b. To separate specific clone of virus
• c. To maintain certain viral culture
• d. To prepare vaccines

2633. All are oncogenic except_______?

• a. Anopheles
• b. Aedes ✅
• c. Culex
• d. Mansoni

2634. DNA covering material in a virus is called as_____?

• a. Capsomere
• b. Capsid ✅
• c. Nucleocapsid
• d. Envelope

2635. All are oncogenic except_______?

• a. EB virus
• b. Papilloma virus
• c. Herpes simplex virus ✅
• d. Varicella zoster virus

2636. True about HIV are all except____?

• a. DNA virus ✅
• b. Attacks CD4 cells
• c. Macrophages are the reservoir
• d. Decrease CD4 count in late stages

2637. EBV causes all except_________?

• a. Carcinoma of nasopharynx
• b. Papilloma ✅
• c. Infectious mononucleosis
• d. Burkitt’s lymphoma

2638. Australian antigen is________?

• a. HB Ag
• b. HBs AG ✅
• c. HBV
• d. None of the above

2639. Which of the following methods is adopted for screening HIV infection ?

• a. Virus isolation
• b. Western blot followed by ELISA
• c. ELISA followed by western blot technique ✅
• d. Polymers chain reaction

2640. Enterically transmitted NANB hepatitis B______?

• a. Hepatitis C
• b. Hepatitis D
• c. Hepatitis E ✅
• d. Hepatitis F

2641. True about immune response of hepatitis B is_______?

• a. Antibody of HBs Ag is associated with resistance to infection ✅
• b. Antibody to HBC is not protective
• c. Highest titres of anti HBC are found in persistent carriers of HBs Ag
• d. CMI disappears soon after recover

2642. The best way of detecting the presence of viruses in the infected cell – culture is______?

• a. Cytopathic changes in culture cells ✅
• b. Presence of viral protein in the infected monolayer
• c. Haemagglutination test
• d. Haemagglutination inhibition test

2643. The Dane particle is the_______?

• a. HBV ✅
• b. IgG anti HAV
• c. Delta Virus
• d. HBC Ag

2644. Baby born to mother suffering from AIDS, all are true except_______?

• a. Failure to thrive
• b. Have infections
• c. 50% chances to have AIDS ✅
• d. All are true

2645. The time gap between appearance of Koplik’s spot and cutaneous rash in measles is_______?

• a. 24 Hrs
• b. 3-4 days ✅
• c. 2 weeks
• d. 10 days

2646. Rabies virus______?

• a. Cytotropic
• b. Dermatotropic
• c. Chromophilic
• d. Neurotropic ✅

2647. Virus are sharply differentiated from bacteria by_____?

• a. Presence of either DNA or RNA
• b. Simple structure
• c. Complex multiplication
• d. All of the above ✅

2648. The following hepatitis virus is transmitted by faeco-oral route_______?

• a. Hepatitis B virus
• b. Hepatitis C virus
• c. Hepatitis D virus
• d. Hepatitis E virus ✅

2649. Confirmatory test for HIV infection is a______?

• a. ELISA
• b. Immunodot
• c. IPA
• d. Western Blot ✅

2650. Bacteriophage was discovered by______?

• a. Robert Koch
• b. Twort and d’herelle ✅
• c. Menkin
• d. Metchinkoff