Cardiac Markers and Acute Myocardial Infarction (AMI) MCQs

1. The earliest marker for diagnosis of acute myocardial infarction within the first 2 hours of onset of chest pain is:
   • A. CK-MB
   • B. AST
   • C. Myoglobin ✅
   • D. cTnT
   • E. LDH


2. Total CK activity is NOT increased in:
   • A. Duchene myopathy
   • B. Hyperthyroidism ✅
   • C. Diabetic ketoacidosis
   • D. Severe muscle exercise
   • E. Acute myocardial infarction


3. Which of the following markers may show increased levels 12 days after an acute myocardial infarction:
   • A. Total CK
   • B. CK-MB
   • C. AST
   • D. LDH ✅
   • E. cTnI


4. To diagnose AMI, the ratio of CK – MB isoenzyme to total CK must exceed:
   • A. 4 %
   • B. 6 %✅
   • C. 8 %
   • D. 10 %
   • E. 20 %


5. The most specific marker for diagnosis of AMI is:
   • A. Myoglobin
   • B. CK-MB
   • C. AST
   • D. LDH
   • E. Cardiac troponins ✅


6. A specific marker which can be used to diagnose AMI in a patient presenting 8 days after the onset of chest pain:
   • A. AST
   • B. Total LDH
   • C. Flipped LDH ratio
   • D. Cardiac troponin I
   • E. Cardiac troponin T ✅


7. One of the following cardiac markers is most useful in ruling out MI:
   • A. CK – MB mass
   • B. LDH isoenzymes
   • C. Troponins (I or T)
   • D. Myoglobin ✅
   • E. CK-total